When the Indianapolis Colts visit the San Francisco 49ers Sunday, the former might have a new running back to help their offense after a huge trade netted them running back Trent Richardson last Wednesday. The 49ers meanwhile are focused in getting back on track after an embarrassing loss to the Seattle Seahawks in their previous outing.

The Colts acquired Richardson, who was the 3rd overall pick in the 2012 NFL Draft, from the Cleveland Browns in exchange for a 2014 first round draft pick. Richardson is expected to suit up against the 49ers.

In his short career with the Browns, he had 950 rushing yards and 11 touchdowns in 15 games in 2012 and 105 rushing yards in 31 carries in 2 games in 2013.

Meanwhile, the 49ers are off their worst loss in years-- a 3-29 loss to NFC West rivals Seattle. Star quarterback Colin Kaepernick was limited to 127 total yards, his lowest total output as an NFL starter, and also had four turnovers.

Both numbers were a far-cry from his Week 1 output when he had 412 passing yards (27-of-39 completions) and 3 TD in a 34-28 win over the Green Bay Packers.

The Colts are also at 1-1 going into Week 3. They lost to won against the Oakland Raiders, 21-17 in their opener and lost to the Miami Dolphins, 20-24 in Week 2.

Betting Against the Spread (ATS)

Indianapolis Colts Trends
- Colts are 8-1 ATS in their last 9 games after a loss
- Colts are 6-2 ATS in their last 8 games after an ATS loss
- Colts are 1-4 in their last 5 games in September

San Francisco 49ers Trends
- 49ers are 19-6-3 ATS in their last 28 games after an ATS loss
- 49ers are 16-6-1 ATS in their last 23 games at home
- 49ers are 6-2-1 ATS in their last 9 games in September

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