Mar 27, 2016; Key Biscayne, FL, USA; Novak Djokovic waves to fans after his match against Joao Sousa (not pictured) during day six of the Miami Open at Crandon Park Tennis Center. Djokovic won 6-4, 6-1. Reuters/Geoff Burke-USA TODAY Sports TPX IMAGES OF THE DAY

Novak Djokovic will take on another tennis rising star in Austria’s Dominic Thiem in Round of 16 of the Miami Open at Crandon Park Tennis Center.

Djokovic will continue his bid for a sixth and third-straight Miami Open title when the Serb meets Thiem in the fourth round of the ATP 1000 Masters tournament in Key Biscayne, Florida. The world No. 1, who has not lost a match in Miami since 2013 and is 26-1 in his past 27 matches at the tournament, dismissed Portuguese Joao Sousa in the third round 6-4 6-1.

“[Sousa] made me play,” Djokovic said, reports the ATP’s official website. “He made me push myself harder in the second set because he was staying close to the baseline and picking up the balls very efficiently, which I wasn't expecting. I thought he was going to be playing from back of the court a little bit more.”

Djokovic has only met Thiem once back in 2014 at the ATP 1000 Masters Shanghai, where the 28-year-old defeated the world No. 14 in straight sets. With little experience in facing the Austrian youngster, Djokovic may have a hard time figuring out Thiem, who defeated Japanese Yoshihito Nishioka 6-2 6-2.

Thiem has been in impressive form this season after winning events in Acapulco and Buenos Aires, which included an upset over world No. 5 Rafael Nadal. But against a Djokovic, the Austrian rising star may need more than luck to get through to the quarterfinals.

"He's a young player who has a lot of potential and a nice variety in his game," Djokovic said of Thiem, reports ESPN.

The winner between Djokovic and Thiem could have a quarterfinal showdown either against Frenchman Richard Gasquet and Czech Tomas Berdych, who battle in the other half of the bracket. Gasquet defeated compatriot Benoit Paire 6-3 6-0, while Berdych escaped American Steve Johnson 6-3 6-7(6) 6-3.

Live streaming info and score updates

Watch the Miami Open 2016 live via ATP’s official website or TennisTV. Live scores for matches will be available on game days via ATP's official website.