'Game of Thrones' actress Emilia Clarke plays Louisa Clark in 'Me Before You' movie
Actress Emilia Clarke arrives at the 22nd Screen Actors Guild Awards in Los Angeles, California January 30, 2016. She stars opposite Sam Claflin in "Me Before You," release date set on June 3 in U.S. cinemas. Reuters/Mike Blake

Emilia Clarke and Sam Claflin thrilled fans who saw the recent release of "Me Before You" trailer on YouTube. Clark sheds off her Daenerys Targaryen skin from her "Game of Thrones" role to play Louisa Clark in the movie adaptation of the romantic novel by Jojo Moyes. Clarke and Claflin's screen chemistry sparked positive reactions on social media sites like Twitter.

"A girl (Louisa Clark) in a small town forms an unlikely bond with a recently-paralyzed man (Will Traynor) she's taking care of," reads the "Me Before You" synopsis on IMDB. Through tweets that made #MeBeforeYouTrailer go viral, fans picked their favorite scenes from the trailer. See some of the tweets below, including an invitation from Sam Claflin.

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Sam Claflin, Emilia Clarke show good chemistry on screen
Cast member Sam Claflin poses at the premiere of "The Hunger Games: Mockingjay - Part 2" in Los Angeles, California November 16, 2015. He stars with Emilia Clarke in the 2016 romantic drama, "Me Before You." Reuters/Mario Anzuoni

Novelist Jojo Moyes also wrote the screenplay of the "Me Before You" movie, which is directed by Thea Sharrock ("Call the Midwife"). The film also stars another "Game of Thrones" actor, Charles Dance. He is portraying Will's father, Steven Traynor, who was not entirely devoted to his family. The romantic drama promises funny and emotional moments, allowing Clarke and Claflin to showcase their acting chops and endear more fans.

As Louisa in "Me Before You," Clarke is bubbly, vibrant and adorable. As Daenerys in "Game of Thrones," the British actress is fierce and powerful, not to mention a mighty mother to three dragons. The contrast in these leading roles allow Clarke to shine in a manner that many actors can only dream of -- in film and television. Reviews and reactions from fans prove that Clarke is able to win their approval by showing personalities in sharp contrast. Moviegoers who enjoyed "The Fault in Our Stars" (which earned US$ 48M on its opening weekend alone in 2014) are expected to line up in cinemas worldwide to see Clarke and Claflin in their remarkable romantic drama.

The "Me Before You" cast also include Janet McTeer, Jenna Coleman, Matthew Lewis and Stephen Peacocke. They are playing Will's mother, Louisa's sister Katrina, Louisa's boyfriend Patrick and Will's friend Nathan, respectively. The movie is produced Metro-Goldwyn-Mayer (MGM) and New Line Cinema.

WATCH: Me Before You – Official Trailer - Official Warner Bros. UK

Source: YouTube/Warner Bros. UK

Meanwhile, fans awaiting the "Game of Thrones" Season 6 release date have viewed the Targaryen storyline teaser video for over a million times on YouTube. In the GOT 6 video, Clarke's Daenerys Targaryen is being mocked as khaleesi or queen of nothing. Watch the teaser below.

WATCH: 'GOT 6' teaser hints Daenerys Targaryen insulted as 'Khaleesi of Nothing'

Source: YouTube/GameOfThrones

In "A Dance with Dragons," the fifth book of "A Song of Ice and Fire" from which "Game of Thrones" is based, Daenerys Targaryen are found by the khalasar of Khal Jhaqo. Daenerys has a score to settle with him, but he and his crew find her in a vulnerable state toward the end of GOT 5. ASOIAF author George R.R. Martin has yet to release the sixth book, "Winds of Winter." This means what happens next to Daenerys in GOT 6 is entirely open for fan theories and speculations.

The "Game of Thrones" Season 6 release date is on April 24. The "Me Before You" movie will premiere on June 3 in US cinemas. If GOT 6 runs for ten weeks in a row, it will overlap with the romantic movie screening. There will be more Emilia Clarke for fans to enjoy.

Here are some of the fans' favourite scenes from the "Me Before You" trailer, plus a tweet from Sam Claflin:

Sam Claflin and wife Laura Haddock expecting first baby
Actor Sam Claflin and partner Laura Haddock pose for photographers on the red carpet at the UK premiere of "The Hunger Games : Mockingjay Part 2" at Leicester Square in London, Britain November 5, 2015. Reuters/Luke MacGregor
Jason Clarke and Emilia Clarke, co-stars in 'Terminator Genisys'
Cast members Jason Clarke and Emilia Clarke attend the premiere of "Terminator Genisys" in Hollywood, California June 28, 2015. Clarke plays Louisa Clark in "Me Before You," release date set on June 3, 2016 in US cinemas. Reuters/Mario Anzuoni