Humans nearing cure for multiple sclerosis with Roche's drug Ocrelizumab

For a number of years, researchers have been trying to figure out a promising treatment option for multiple sclerosis (MS). Recently conducted clinical trial for Roche's new drug suggest that a reliable treatment option for late-stage MS patients could be just around the corner.
Roche Holding AG’s Genentech unit recently claimed that its new drug dubbed “Ocrelizumab” has proved to be effective against the treatment of MS in the three-phase clinical trial. The company believes that the successful trials could pave way for a new, revolutionary treatment for MS.
According to Genetech, Ocrelizumab reduces the chances of annual MS relapse by almost 50 percent, as compared to its older counterpart called interferon beta-1a (Rebif). Genetech's chief medical officer Sandra Horning says that the drug is first of its own kind to reduce the progression of disability in people with relapsing and primary form of MS.
In the first two major studies involving 1,656 patients with relapsing MS, the trial found that Ocrelizumab significantly reduced annual rate of relapse of major symptoms and other markers associated with the disease. The third stage study, which involved 732 patients with primary progressive multiple sclerosis, the drug successfully slowed down the progression of disability as compared to a placebo.
Roche and Genentech are planning to submit the data associated with the study to the U.S. Food and Drug Administration by early 2016. If the companies get regulatory approval, the drug could hit the market as early as 2017.
MS affects nearly 2.3 million people in the world. In this disease, body's own immune patients attack the protective sheath that coat the nerve fibres. As a result, transmission of signals between the brain and the spinal cord is disrupted.
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