Five-time US Open champion Roger Federer faces big-serving and highest-ranked American John Isner in the fourth round of the 2015 US Open. Federer, who is bidding to win his 18th grand slam trophy, leads their head-to-head series 4-1.

Federer’s most recent win was a straight-sets victory over No. 29 seed Philipp Kohlschreiber 6-3 6-4 6-4 at Arthur Ashe on day six of the main draw of the 2015 US Open. The victory marked Federer’s 75th career singles win. It is the 15th consecutive year that the 17-time grand slam champion had advanced in the fourth round at Flushing Meadows.

The No. 2 seed is yet to lose a set in the tournament. He struck 27 aces and 102 winners in his previous matches. He had 64 double faults. Federer, who turned 34 in August, has delighted the New York crowd by firing the right combination to keep his opponents at their feet. Only in his last match with Kohlschreibe