Apart from Anne Hathaway's nip moment at the Academy Awards, another celebrity caused a Twitter debate. Renee Zellweger appeared on the Oscars stage last Sunday looking all smooth in the face, not a wrinkle is in sight.

At 43, it's to be expected to see some visible signs of aging but Renee Zellweger appeared looking more "wrinkle free" than she did 10 years ago. What's the secret? Botox. Her incredibly smooth face has caused fans to debate on Twitter and other social networking sites that Rene may have overdone it.

Renee appeared on stage together with Catherine Zeta-Jones, Richard Gere and Queen Latifah to present an award that night. For the joyous moment on stage, Renee looks like she's having a hard time smiling and grinning while appearing "too stretched" on the face.

Apart from the thousands and millions of Twitter users who tuned in for the Oscars on Sunday, "Modern Family" actor Jesse Tyler Ferguson tweeted his reaction about Renee's Botox face.

"Renee Zellweger arrives as a Ghost of Christmas Future for Jennifer Lawrence, bearing warning about Botox. #Oscars2013 " he said.

Botox has long been used by Hollywood actors and actresses to erase the signs of aging. Since they work in a business where good looks is a priority, some stars have resorted to Botox for a quick face fix.

There are other celebrities like Nicole Kidman, Jennifer Aniston and Kelly Ripa who admitted that they have tried the procedure. But although the results can work as a temporary solution, Botox is still considered quite an embarrassment in Hollywood.

Browse through the slideshow and see other Hollywood celebrities who have tried Botox.