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“Grey’s Anatomy” Season 11 looks closer into Meredith’s marriage in this week’s new episode titled, “I Feel the Earth Move” aka Greys 11x15. Meanwhile, Owen Hunt begins a new romance with someone in Meredith’s family. IN PHOTO: The cast of the ABC drama series "Grey's Anatomy" poses with their award for Favorite Network TV Drama during the 2015 People's Choice Awards in Los Angeles, California January 7, 2015. REUTERS/Danny Moloshok

“Grey’s Anatomy” Season 11 returns with a new episode on ABC this Thursday, April 30. Camilla Luddington, who plays Jo Wilson on the series, dished teasers about it on Twitter. Meanwhile, Joe Adler and Giacomo Gianniotti, from CBS’ “The Mentalist” and The CW’s “Reign” respectively, are stepping in Grey Sloan Memorial as guest stars.

Spoiler alert: This update contains “Grey’s Anatomy” Season 11 spoilers. Read on at your own risk.

Episode 22 of “Grey’s Anatomy” Season 11 is titled “She’s Leaving Home.” This is a special 2-hour episode that follows an emotional event in the Shondaland drama: the death of Derek Shepherd aka McDreamy (Patrick Dempsey).

In a tweet, Luddington hinted at big moments in “Grey’s Anatomy” Season 11, episode 22. Still on Twitter, the actress responded to an all-caps message from a follower, asking “what else” can happen. To this, Luddington replied, “a lot” can happen in the ABC medical drama. (See her tweets below.)

Luddington’s Jo Wilson is Alex Karev’s (Justin Chambers) girlfriend on “Grey’s Anatomy.” The couple has not faced any serious problems in the show’s recent timeline. It remains to be seen whether they figure in something bigger in the final episodes of Season 11.

Camilla Luddington Answers: What Happens Next After Derek Shepherd’s Death?

Camilla Luddington Tweets About ‘Grey’s Anatomy’ Season 11, Episode 22

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Meanwhile, Joe Adler and Giacomo Gianniotti will be seen in the next new episode(s) of “Grey’s Anatomy” Season 11. TVLine reported Adler will be in the story arc for the season finale. Adler played Jason Wylie in CBS’ “The Mentalist.”

TVLine’s Michael Ausiello is guessing Gianniotti is playing the role of a new intern at Grey Sloan Memorial. He also said Gianniotti may be playing a recurring character. Gianniotti played Remy/Lord Julien in “Reign.”

“Grey’s Anatomy” Season 11, episode 21 airs Thursdays on ABC. This week, it takes the primetime slot of “Scandal.”

Let us know your thoughts on “Grey’s Anatomy” Season 11. For questions/comments regarding the article, you may email the writer at a.paredes@ibtimes.com.au.