New residents are coming to meddle in the present issues in Seattle Grace.

"True Blood" Vadette Lim and "Gossip Girl" Holley Fain will be guest starring in the coming episodes of ABC's "Grey's Anatomy". She will appear first in the eighth episode of "Grey's Anatomy".

According to TVGuide.com, Vadette Lim will be a competition for Alex (Justin Chambers) as she will be playing Dr. Polly Preston with a pediatric fellowship. Arizona (Jessica Capshaw) will like Polly and will ditch Alex from her cases.

Lim previously played Tara's lesbian lover on the fourth season of HBO series "True Blood".

Former "Gossip Girl" actress Holley Fain will stir the going steady relationship of Mark Sloane and Lexi.

According to TVLine.com, Holley Fain will be a recurring love interest for Eric Dane's rebounding doc. Fain is an ophthalmologist in another Seattle-based hospital under Ernie Hudson. Fain's character will appear in the November episode.

Holley Fain appeared in "Gossip Girl" as Madeline Vanderbilt, the manipulative wife of Nate's cousin Tripp. She also appeared in "The Good Wife," "Memphis Beat" and "Law & Order: Criminal Intent".

Catch Grey's Anatomy on Thursdays, 9PM EST/PST at ABC.

Arizona